Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187160 | 0.76 | HRH1 (0.49) | KCNH2HRH3LTA4H | |
| SCHEMBL11782167 | 0.70 | LTA4H (0.62) | KCNH2HRH3LTA4HACKR3 | |
| SCHEMBL132013 | 0.70 | KCNH2 (0.49) | KCNH2HRH3LTA4H | |
| SCHEMBL13517962 | 0.68 | KCNH2 (0.50) | KCNH2HRH3LTA4H | |
| SCHEMBL15976794 | 0.68 | KCNH2 (0.50) | KCNH2HRH3LTA4HACKR3 | |
| SCHEMBL20410952 | 0.65 | KCNH2 (0.43) | KCNH2HRH3LTA4H | |
| SCHEMBL9219942 | 0.65 | KCNH2 (0.54) | KCNH2HRH3LTA4HACKR3 | |
| SCHEMBL23576315 | 0.64 | KCNH2 (0.47) | KCNH2HRH3LTA4HACKR3 | |
| SCHEMBL9668080 | 0.64 | HRH3 (0.68) | KCNH2HRH3LTA4HACKR3 | |
| SCHEMBL9212204 | 0.64 | KCNH2 (0.53) | KCNH2HRH3LTA4HACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097334-A1 | DRUG COMBINATIONS CONTAINING PDE4 INHIBITORS AND NSAIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |