Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.48 |
| ▸ | RARG | P13631 | 9/20 | 0.48 |
| ▸ | RARA | P10276 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929851 | 0.93 | RARB (0.45) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7930122 | 0.90 | HIF1A (0.43) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7927690 | 0.89 | RARB (0.43) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7926559 | 0.88 | RARB (0.44) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL8458430 | 0.85 | HIF1A (0.41) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7927824 | 0.84 | HIF1A (0.43) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7927274 | 0.81 | HIF1A (0.40) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7926544 | 0.79 | HIF1A (0.39) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL8459706 | 0.77 | PTPN11 (0.41) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7929547 | 0.75 | RARB (0.43) | RARBRARGRARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225328-B1 | FOR THERAPY OF DISORDERS OR AILMENTS RELATED TO AN OVERREGULATION OF RETINOIC ACID RECEPTORS AND/OR TO HYPERVIAMINOSIS A | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-05-01 | — | — | US | disclosed |