Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918859 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MTNR1AMTNR1BCNR2TSHR | |
| SCHEMBL7911810 | 0.91 | ALDH1A1 (0.39) | ALDH1A1MTNR1AMTNR1BCNR2MAPT | |
| SCHEMBL7911920 | 0.91 | ALDH1A1 (0.39) | ALDH1A1MTNR1AMTNR1BCNR2MAPT | |
| SCHEMBL7924000 | 0.86 | CNR2 (0.37) | ALDH1A1CNR2TSHRMAPTHSD17B10 | |
| SCHEMBL7920572 | 0.86 | CNR2 (0.37) | ALDH1A1CNR2TSHRMAPTHSD17B10 | |
| SCHEMBL7918967 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MTNR1AMTNR1BTSHRMAPT | |
| SCHEMBL9366549 | 0.82 | MTNR1A (0.43) | ALDH1A1MTNR1AMTNR1BTSHRMAPT | |
| SCHEMBL7918943 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MTNR1AMTNR1BTSHRMAPT | |
| SCHEMBL7911874 | 0.78 | ALDH1A1 (0.62) | ALDH1A1TSHRMAPTHSD17B10 | |
| SCHEMBL7911884 | 0.78 | MAPT (0.47) | ALDH1A1CNR2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811375-B1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA LTD (JP) | 2001-01-03 | — | — | EP | disclosed |
| EP-0811375-A1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA, LTD. (JP) | 1997-12-10 | — | — | EP | disclosed |
| EP-0469901-B1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5189211-A | Thromboxane A2 antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1993-02-23 | — | — | US | disclosed |
| EP-0469901-A1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1992-02-05 | — | — | EP | disclosed |