Fluoranthene

Fluoranthene

SCHEMBL7921020

c1ccc2c(c1)-c1cccc3cccc-2c13.c1ccc2cc3ccccc3cc2c1

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.83
HSD17B10 Q99714 7/20 0.83
MAPK1 P28482 4/20 0.83
TSHR P16473 4/20 0.83
L3MBTL1 Q9Y468 2/20 0.83
ATM Q13315 2/20 0.83
HPGD P15428 4/20 0.80
CASP1 P29466 3/20 0.80
CASP7 P55210 2/20 0.80
HIF1A Q16665 2/20 0.80
TP53 P04637 1/20 0.80
PABPC1 P11940 3/20 0.62
CYP3A4 P08684 2/20 0.62
DNMT1 P26358 2/20 0.62
CES1 P23141 2/20 0.52
CES2 O00748 1/20 0.52
BCHE P06276 1/20 0.52
MCL1 Q07820 1/20 0.52
KDM4E B2RXH2 2/20 0.48
TYMS P04818 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrene SCHEMBL27541102 0.95 ALDH1A1 (0.75) ALDH1A1HSD17B10MAPK1TSHRL3MBTL1
Fluoranthene SCHEMBL27152 0.91 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1TSHRL3MBTL1
Fluoranthene SCHEMBL29396242 0.91 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1TSHRL3MBTL1
Fluoranthene SCHEMBL8873541 0.91 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1TSHRL3MBTL1
Fluoranthene SCHEMBL29355720 0.91 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1TSHRL3MBTL1
SCHEMBL23525587 0.91 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1TSHRL3MBTL1
SCHEMBL4853854 0.90 ALDH1A1 (0.90) ALDH1A1HSD17B10MAPK1TSHRL3MBTL1
Benzo(K)Fluoranthene SCHEMBL175484 0.89 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1TSHRL3MBTL1
Benzo(K)Fluoranthene SCHEMBL29393074 0.89 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1TSHRL3MBTL1
Fluoranthene SCHEMBL30911873 0.88 ALDH1A1 (0.94) ALDH1A1HSD17B10MAPK1TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1124671-A1 BIO-OIL PRESERVATIVES Ensyn Technologies Inc. (CA) 2001-08-22 EP claimed
WO-2000025996-A1 BIO-OIL PRESERVATIVES ENSYN TECHNOLOGIES INC. (CA) 2000-05-11 WO claimed
CN-110785376-B Surface-modified inorganic nitride, composition, heat-conducting material and device with heat-conducting layer 富士胶片株式会社 2023-03-31 CN disclosed
CN-115193081-A System and method for efficiently and environmentally extracting crude anthracene 武汉宝聚炭材料有限公司 2022-10-18 CN disclosed