Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.44 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7923735 | 0.86 | SMN1; SMN2 (0.45) | ALDH1A1CYP1A2CYP3A4CYP2C9NFKB1 | |
| SCHEMBL9510805 | 0.85 | TBXA2R (0.60) | TBXA2RTBXAS1SGMS1 | |
| SCHEMBL2925987 | 0.83 | ALDH1A1 (0.69) | TBXA2RPTGDR2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7924088 | 0.82 | TBXA2R (0.45) | TBXA2RPTGDR2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9512730 | 0.75 | TBXA2R (0.58) | TBXA2RTBXAS1SGMS1 | |
| SCHEMBL9510541 | 0.75 | TBXA2R (0.59) | TBXA2RALDH1A1TBXAS1SGMS1TP53 | |
| SCHEMBL9513246 | 0.75 | TBXA2R (0.50) | TBXA2RPTGDR2TBXAS1SGMS1 | |
| SCHEMBL7919301 | 0.74 | SGMS1 (0.47) | TBXA2RALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7919051 | 0.73 | ALDH1A1 (0.72) | TBXA2RALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7920584 | 0.73 | ALDH1A1 (0.81) | TBXA2RALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811375-B1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA LTD (JP) | 2001-01-03 | — | — | EP | disclosed |
| EP-0811375-A1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA, LTD. (JP) | 1997-12-10 | — | — | EP | disclosed |