Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918930 | 0.89 | ALDH1A1 (0.56) | MEN1KMT2ACA1CA2TBXA2R | |
| SCHEMBL7919333 | 0.88 | MEN1 (0.54) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL7911879 | 0.84 | MEP1B (0.53) | MEN1KMT2ATBXA2RALDH1A1MAPT | |
| SCHEMBL7911878 | 0.84 | TBXA2R (0.70) | MEN1KMT2ATBXA2RALDH1A1MAPT | |
| SCHEMBL7911851 | 0.84 | ALDH1A1 (0.70) | MEN1KMT2ATBXA2RALDH1A1MAPT | |
| SCHEMBL7918909 | 0.83 | ALDH1A1 (0.56) | MEN1KMT2ATBXA2RALDH1A1MAPT | |
| SCHEMBL7919294 | 0.81 | ALDH1A1 (0.56) | MEN1KMT2ATBXA2RALDH1A1GAA | |
| SCHEMBL8442665 | 0.80 | ALDH1A1 (0.58) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL7918975 | 0.78 | ALDH1A1 (0.47) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL7919315 | 0.78 | ALDH1A1 (0.60) | MEN1KMT2ACA1CA2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811375-B1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA LTD (JP) | 2001-01-03 | — | — | EP | disclosed |
| EP-0811375-A1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA, LTD. (JP) | 1997-12-10 | — | — | EP | disclosed |
| EP-0469901-B1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5189211-A | Thromboxane A2 antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1993-02-23 | — | — | US | disclosed |
| EP-0469901-A1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1992-02-05 | — | — | EP | disclosed |