Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921075 | 0.81 | GPBAR1 (0.53) | GPBAR1CYSLTR1CYSLTR2PLA2G1BFFAR1 | |
| SCHEMBL7593150 | 0.76 | GPBAR1 (0.56) | GPBAR1CYSLTR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL9081199 | 0.75 | CYSLTR1 (0.61) | GPBAR1CYSLTR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL9847314 | 0.75 | CYSLTR1 (0.58) | GPBAR1CYSLTR1CYSLTR2PLA2G1B | |
| SCHEMBL28030524 | 0.74 | NPC1 (0.57) | GPBAR1CYSLTR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL9305654 | 0.74 | CYSLTR1 (0.49) | GPBAR1CYSLTR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL9632083 | 0.74 | GPBAR1 (0.48) | GPBAR1CYSLTR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL7504604 | 0.73 | CYSLTR1 (0.58) | GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL8834234 | 0.72 | GPBAR1 (0.57) | GPBAR1CYSLTR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL10438452 | 0.71 | GPBAR1 (0.50) | GPBAR1CYSLTR1CYSLTR2PLA2G1BFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414019-B1 | Subsituted N-(quinolin-2-yl-methoxy)benzylsulfonylureas | BAYER AG (DE) | 1996-05-29 | — | — | EP | claimed |
| US-5179106-A | SUBSTITUTED N-(QUINOLIN-2-YL-METHOXY) BENZYL-SULPHONYLUREA LEUKOTRIENE SYNTHESIS INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-01-12 | — | — | US | claimed |
| CN-1040440-C | Preparation method of dehydrocycloclausenamide derivative | BAYER AG (DE) | 1998-10-28 | — | — | CN | disclosed |
| EP-0414019-B1 | Subsituted N-(quinolin-2-yl-methoxy)benzylsulfonylureas | BAYER AG (DE) | 1996-05-29 | — | — | EP | disclosed |
| US-5179106-A | SUBSTITUTED N-(QUINOLIN-2-YL-METHOXY) BENZYL-SULPHONYLUREA LEUKOTRIENE SYNTHESIS INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-01-12 | — | — | US | disclosed |
| US-5179106-A | SUBSTITUTED N-(QUINOLIN-2-YL-METHOXY) BENZYL-SULPHONYLUREA LEUKOTRIENE SYNTHESIS INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-01-12 | — | — | US | disclosed |
| EP-0414019-A2 | Subsituted N-(quinolin-2-yl-methoxy)benzylsulfonylureas | BAYER AG (DE) | 1991-02-27 | — | — | EP | disclosed |
| EP-0414019-A2 | Subsituted N-(quinolin-2-yl-methoxy)benzylsulfonylureas | BAYER AG (DE) | 1991-02-27 | — | — | EP | disclosed |