Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 18/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924138 | 0.88 | ALDH1A1 (0.67) | TBXAS1ALDH1A1MAPTTBXA2R | |
| SCHEMBL7919317 | 0.81 | TBXAS1 (0.54) | TBXAS1ALDH1A1TBXA2R | |
| SCHEMBL7911859 | 0.81 | ALDH1A1 (0.67) | TBXAS1ALDH1A1MAPTTBXA2R | |
| SCHEMBL7924112 | 0.81 | ALDH1A1 (0.60) | TBXAS1ALDH1A1MAPTTBXA2R | |
| SCHEMBL7911899 | 0.81 | ALDH1A1 (0.64) | TBXAS1ALDH1A1MAPTTBXA2R | |
| SCHEMBL7911872 | 0.81 | ALDH1A1 (0.64) | TBXAS1ALDH1A1MAPT | |
| SCHEMBL9485295 | 0.80 | TBXAS1 (0.53) | TBXAS1ALDH1A1TBXA2R | |
| SCHEMBL7920590 | 0.79 | ALDH1A1 (0.62) | TBXAS1ALDH1A1MAPT | |
| SCHEMBL7918930 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTTBXA2R | |
| SCHEMBL9718380 | 0.77 | TBXAS1 (0.63) | TBXAS1ALDH1A1MAPTTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811375-B1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA LTD (JP) | 2001-01-03 | — | — | EP | disclosed |
| EP-0811375-A1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA, LTD. (JP) | 1997-12-10 | — | — | EP | disclosed |
| EP-0469901-B1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1994-10-19 | — | — | EP | disclosed |
| EP-0469901-A1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1992-02-05 | — | — | EP | disclosed |