Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2785848 | 0.92 | PPARG (0.46) | PPARGPPARA | |
| SCHEMBL7920692 | 0.90 | PPARG (0.50) | PPARGPPARAPPARD | |
| Trifluoroacetic Acid SCHEMBL7705739 | 0.89 | PPARG (0.43) | PPARGPPARA | |
| SCHEMBL7926603 | 0.83 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL2786491 | 0.82 | PPARG (0.53) | PPARGPPARA | |
| SCHEMBL7921358 | 0.82 | PPARG (0.69) | PPARGPPARA | |
| SCHEMBL7923377 | 0.80 | PPARG (0.49) | PPARGPPARAPPARD | |
| Trifluoroacetic Acid SCHEMBL7711566 | 0.79 | PPARG (0.50) | PPARGPPARA | |
| SCHEMBL7922719 | 0.78 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL7922696 | 0.77 | PPARG (0.64) | PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888317-B1 | SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA | GLAXO GROUP LTD (GB) | 2001-09-12 | — | — | EP | disclosed |
| EP-0888317-A1 | SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA | GLAXO GROUP LIMITED (GB) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997031907-A1 | SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA | GLAXO GROUP LIMITED (GB) | 1997-09-04 | — | — | WO | disclosed |