Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | TSHR | P16473 | 5/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921570 | 0.90 | LMNA (0.61) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL7915574 | 0.88 | LMNA (0.58) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL7921561 | 0.86 | LMNA (0.56) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL7921558 | 0.86 | LMNA (0.56) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL7923488 | 0.85 | LMNA (0.53) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL7924018 | 0.85 | ALDH1A1 (0.58) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL7921472 | 0.85 | LMNA (0.58) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL7921592 | 0.84 | LMNA (0.54) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL7921621 | 0.84 | ALDH1A1 (0.76) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL7921763 | 0.83 | LMNA (0.56) | LMNAALDH1A1TSHRTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |