Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 14/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3472814 | 0.87 | CYP1A2 (0.47) | MPLMTNR1AMTNR1BCYP1A2CYP2A6 | |
| SCHEMBL2328914 | 0.84 | MTNR1A (0.49) | MTNR1AMTNR1BHTR2CHTR2BHTR2A | |
| SCHEMBL10296073 | 0.83 | MTNR1A (0.54) | MTNR1AMTNR1B | |
| SCHEMBL12086546 | 0.81 | MPL (0.51) | MPLMTNR1A | |
| Sulfuric Acid SCHEMBL9250308 | 0.79 | MTNR1A (0.55) | MTNR1AMTNR1BHTR2CHTR2BHTR2A | |
| SCHEMBL686665 | 0.78 | TTR (0.55) | MPLCYP1A2 | |
| SCHEMBL12406605 | 0.78 | CYP1A2 (0.53) | MPLCYP1A2CYP2A6 | |
| Methoxymethane SCHEMBL28942396 | 0.78 | F2 (0.55) | CYP1A2 | |
| SCHEMBL29623319 | 0.77 | TTR (0.50) | MPLCYP1A2 | |
| SCHEMBL155232 | 0.77 | TTR (0.50) | MPLCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281227-B1 | INHIBITORS OF THE ACTIVITY OF FACTOR XA. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-28 | — | — | US | disclosed |