Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL9480703 | 0.93 | MTNR1A (0.51) | MTNR1AMTNR1BHTR2CHTR2BHTR2A | |
| SCHEMBL249717 | 0.90 | CYP1A2 (0.55) | MTNR1AHTR2AKDM4EMEN1TDP2 | |
| SCHEMBL29792825 | 0.90 | CYP1A2 (0.55) | MTNR1AHTR2AKDM4EMEN1TDP2 | |
| Ethane SCHEMBL12612037 | 0.89 | CYP1A2 (0.53) | MTNR1AMTNR1BHTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL10993696 | 0.89 | CYP1A2 (0.53) | MTNR1AHTR2AKDM4EMEN1TDP2 | |
| SCHEMBL7758710 | 0.83 | ALDH1A1 (0.47) | MTNR1AKDM4EMEN1TDP2ALDH1A1 | |
| SCHEMBL7921792 | 0.79 | MPL (0.54) | MTNR1AMTNR1BHTR2CHTR2BHTR2A | |
| SCHEMBL7717478 | 0.79 | CA1 (0.45) | MTNR1AKDM4EMEN1TDP2ALDH1A1 | |
| SCHEMBL5746405 | 0.79 | CYP1A2 (0.55) | MTNR1AHTR2AMEN1ALDH1A1MAPT | |
| SCHEMBL5747140 | 0.79 | CYP1A2 (0.55) | MTNR1AHTR2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369219-B1 | Light-sensitive compounds, preparation of a light-sensitive mixture therewith and a recording material | HOECHST AG (DE) | 1995-01-04 | — | — | EP | disclosed |
| EP-0413201-B1 | Process for the preparation of 7-hydroxy-1,2-naphthoquinone-(2)-diazide-4-sulfonic acid or salts thereof and their use | HOECHST AG (DE) | 1994-10-26 | — | — | EP | disclosed |
| EP-0413200-B1 | Substituted 1,2-naphthoquinone-(2)-diazide-4-sulfonic acids, process for their production and their use | HOECHST AG (DE) | 1994-10-05 | — | — | EP | disclosed |
| US-5192640-A | Nitrosation, sulfonation, reduction, oxidation, diazotization, and salt formation | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-09 | — | — | US | disclosed |
| US-5077395-A | Nitrosation, sulfonation, reduction, oxidation, diazotization, alkylation or acylation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-12-31 | — | — | US | disclosed |
| EP-0413201-A1 | Process for the preparation of 7-hydroxy-1,2-naphthoquinone-(2)-diazide-4-sulfonic acid or salts thereof and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-20 | — | — | EP | disclosed |
| EP-0413200-A1 | Substituted 1,2-naphthoquinone-(2)-diazide-4-sulfonic acids, process for their production and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-20 | — | — | EP | disclosed |
| EP-0369219-A1 | Light-sensitive compounds, preparation of a light-sensitive mixture therewith and a recording material | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-23 | — | — | EP | disclosed |