SCHEMBL7921886

SCHEMBL7921886

[NH]C(=O)Nc1ccc(O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.60
ALDH1A1 P00352 4/20 0.60
CYP1A1 P04798 2/20 0.60
KMT2A Q03164 2/20 0.60
PEPD P12955 1/20 0.60
MEN1 O00255 1/20 0.60
CA12 O43570 1/20 0.60
BRD4 O60885 1/20 0.60
NR1I2 O75469 1/20 0.60
CA1 P00915 1/20 0.60
CA2 P00918 1/20 0.60
MB P02144 1/20 0.60
CA3 P07451 1/20 0.60
CYP3A4 P08684 1/20 0.60
RARG P13631 1/20 0.60
TSHR P16473 1/20 0.60
ALOX5AP P20292 1/20 0.60
CA4 P22748 1/20 0.60
CA7 P43166 1/20 0.60
NR1I3 Q14994 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6395775 0.79 GAA (0.78) MAPTALDH1A1CYP1A1KMT2APEPD
SCHEMBL11327346 0.79 MAOA (0.82) MAPTALDH1A1CYP1A1KMT2APEPD
SCHEMBL10332579 0.78 MEN1 (0.61) MAPTALDH1A1KMT2AMEN1CA12
SCHEMBL2795008 0.78 NPC1 (0.61) MAPTALDH1A1KMT2AMEN1CA12
SCHEMBL2007282 0.78 TDP1 (0.64) MAPTALDH1A1KDM4ENPC1RAB9A
SCHEMBL333794 0.78 ALDH1A1 (0.61) MAPTALDH1A1KMT2AMEN1CA12
SCHEMBL612152 0.77 MAOA (0.64) MAPTALDH1A1CYP1A1KMT2APEPD
SCHEMBL68444 0.77 EPHX2 (0.64) MAPTALDH1A1KMT2ACYP3A4TSHR
SCHEMBL8476851 0.76 KMT2A (0.60) ALDH1A1KMT2AMEN1CA12CA1
SCHEMBL16677959 0.76 NQO2 (0.84) MAPTALDH1A1CYP1A1KMT2APEPD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6238831-B1 COATING SOLUTION FOR THE PREPARATION OF A PRINTING PLATE COMPRISING PHOTOSENSITIVE MATERIAL AND A THERMOPLASTIC RESIN INSOLUBLE AT ALKALINE PH BOTH HOMOGENOUSLY DISSOLVED IN SOLVENT KODAK POLYCHROME GRAPHICS LLC 2001-05-29 US disclosed