Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 6/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7926124 | 0.81 | BACE1 (0.33) | KDM1ABACE1 | |
| SCHEMBL12204239 | 0.81 | ASIC3 (0.32) | ASIC3 | |
| SCHEMBL7926460 | 0.80 | BACE1 (0.38) | KDM1AASIC3BACE1TDP2APP | |
| SCHEMBL7924449 | 0.76 | PNMT (0.32) | BACE1 | |
| SCHEMBL7925938 | 0.75 | BACE1 (0.39) | KDM1AASIC3BACE1APP | |
| SCHEMBL7925260 | 0.70 | ASIC3 (0.42) | KDM1AASIC3BACE1TDP2APP | |
| SCHEMBL7919559 | 0.67 | TAAR1 (0.52) | BACE1 | |
| SCHEMBL7922745 | 0.67 | TAAR1 (0.52) | BACE1 | |
| SCHEMBL7923623 | 0.65 | PNMT (0.42) | KDM1AASIC3BACE1TDP2APP | |
| SCHEMBL16605597 | 0.63 | HSD17B3 (0.42) | KDM1AASIC3BACE1TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042473-A1 | BIARYL SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |