Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11141496 | 0.97 | TSHR (0.48) | TTRTSHRFFAR4LPAR1LPAR5 | |
| SCHEMBL10740183 | 0.91 | TTR (0.47) | TTRFFAR4LTA4HHTR2ASLC6A4 | |
| SCHEMBL11159132 | 0.88 | APP (0.47) | TTRFFAR4 | |
| SCHEMBL10432985 | 0.88 | TTR (0.41) | TTRFFAR4LTA4HHTR2ASLC6A4 | |
| SCHEMBL9558218 | 0.87 | RIPK1 (0.41) | TTRFFAR4HTR2ASLC6A4LPAR1 | |
| SCHEMBL10361910 | 0.87 | TTR (0.40) | TTRFFAR4LPAR1LPAR5POLB | |
| SCHEMBL9558602 | 0.85 | FFAR4 (0.44) | FFAR4LPAR1LPAR5 | |
| Hydrochloric Acid SCHEMBL8695686 | 0.85 | IDO1 (0.47) | HRH1CYP3A4 | |
| SCHEMBL10361908 | 0.84 | TTR (0.42) | TTRFFAR4HTR2ASLC6A4LPAR1 | |
| SCHEMBL10654097 | 0.84 | TTR (0.39) | TTRFFAR4HTR2ASLC6A4LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | claimed |
| EP-0024612-B1 | NEW 4-FLUORO-3-PHENOXY-BENZYL-ETHERS, PROCESS FOR THEIR PREPARATION AND THEIR USE | BAYER AG (DE) | 1983-10-05 | — | — | EP | claimed |
| US-4381412-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-04-26 | — | — | US | claimed |
| US-RE37087-E1 | 1-(4-ETHOXYPHENYL)-4-(4-FLUORO-3-PHENOXYPHENYL)-1 -TRIFLUOROMETHYLBUTANE OR 1-(4-ETHOXY-3-FLUOROPHENYL)-4-(3-PHENOXYPHENYL)-1-TRIFLUOROMETHYLBUTANE, FOR EXAMPLE; COMBATS INSECTS AND MITES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | disclosed |
| CN-1020449-C | INSECTICIDAL TRIFFLUORMETHYL ALKANE DERIVATIVES | SCHERING AG (DE) | 1993-05-05 | — | — | CN | disclosed |
| EP-0233834-B1 | INSECTICIDAL TRIFLUORMETHYL ALKANE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-04-22 | — | — | EP | disclosed |
| EP-0233834-A1 | Insecticidal trifluormethyl alkane derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-08-26 | — | — | EP | disclosed |
| CN-87100438-A | insecticidal trifluoromethyl alkane derivatives | — | 1987-08-12 | — | — | CN | disclosed |
| EP-0216228-A1 | Oxetane and thietane derivatives having pesticidal properties | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-04-01 | — | — | EP | disclosed |
| US-4381412-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-04-26 | — | — | US | disclosed |
| US-4381412-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-04-26 | — | — | US | disclosed |
| US-4326087-A | REACTING 3-BROMO-4-FLUORO-BENZYL ALCOHOL WITH A CHLORINATING OR BROMINATING AGENT OR 3-BROMO-4-FLUORO-BENZOYL FLUORIDE WITH A HYDRIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-20 | — | — | US | disclosed |
| EP-0024612-A2 | New 4-fluoro-3-phenoxy-benzyl-ethers, process for their preparation and their use | BAYER AG (DE) | 1981-03-11 | — | — | EP | disclosed |