SCHEMBL10361908

SCHEMBL10361908

CC(C)(Cl)COCc1ccc(F)c(Oc2ccccc2)c1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.42
TACR1 P25103 1/20 0.36
RIPK1 Q13546 1/20 0.36
LPAR1 Q92633 1/20 0.35
LPAR5 Q9H1C0 1/20 0.35
HTR2A P28223 1/20 0.35
SLC6A4 P31645 1/20 0.35
FFAR4 Q5NUL3 1/20 0.34
EGLN2 Q96KS0 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9558218 0.89 RIPK1 (0.41) TTRTACR1RIPK1LPAR1LPAR5
SCHEMBL10361910 0.89 TTR (0.40) TTRLPAR1LPAR5FFAR4CYP1A2
SCHEMBL9681472 0.87 TTR (0.43) TTRTACR1RIPK1LPAR1LPAR5
SCHEMBL10837667 0.87 TACR1 (0.42) TTRTACR1RIPK1LPAR1LPAR5
SCHEMBL10654097 0.87 TTR (0.39) TTRTACR1RIPK1LPAR1LPAR5
SCHEMBL10655931 0.86 TTR (0.38) TTRTACR1RIPK1LPAR1LPAR5
SCHEMBL9683220 0.86 TTR (0.38) TTRTACR1RIPK1LPAR1LPAR5
SCHEMBL10836737 0.85 TTR (0.39) TTRTACR1RIPK1LPAR1LPAR5
SCHEMBL10439067 0.85 TTR (0.39) TTRTACR1RIPK1LPAR1LPAR5
SCHEMBL9029398 0.85 TTR (0.39) TTRTACR1RIPK1HTR2ASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0175377-B1 AN ETHER COMPOUND, ITS PRODUCTION AND AN INSECTICIDAL AND ACARICIDAL COMPOSITION CONTAINING IT AS AN ACTIVE INGREDIENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-11-28 EP disclosed
US-4664698-A Ether compound, and an insecticidal and acaricidal composition containing it as an active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-05-12 US disclosed
EP-0175377-A2 An ether compound, its production and an insecticidal and acaricidal composition containing it as an active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-03-26 EP disclosed