Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 3/20 | 0.34 |
| ▸ | ACACA | Q13085 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560885 | 0.83 | LTA4H (0.42) | LTA4HMAPK1CETPKCNH2ACACB | |
| SCHEMBL9714593 | 0.82 | LTA4H (0.41) | LTA4HMAPK1CETPKCNH2ACACB | |
| SCHEMBL10654295 | 0.82 | LTA4H (0.41) | LTA4HKCNH2ACACBACACACNR2 | |
| SCHEMBL10647718 | 0.82 | LTA4H (0.41) | LTA4HKCNH2ACACBACACACNR2 | |
| SCHEMBL7931627 | 0.79 | CETP (0.49) | LTA4HCETP | |
| SCHEMBL10549191 | 0.77 | LTA4H (0.44) | LTA4HMAPK1KCNH2PPARAKDM4E | |
| SCHEMBL9804469 | 0.77 | LTA4H (0.42) | LTA4HMAPK1CETPPPARGPPARD | |
| SCHEMBL9804535 | 0.76 | LTA4H (0.41) | LTA4HMAPK1CETPACACBACACA | |
| SCHEMBL9335440 | 0.76 | LTA4H (0.46) | LTA4HMAPK1KCNH2ACACBACACA | |
| SCHEMBL10657211 | 0.74 | LTA4H (0.39) | LTA4HMAPK1KCNH2PPARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37087-E1 | 1-(4-ETHOXYPHENYL)-4-(4-FLUORO-3-PHENOXYPHENYL)-1 -TRIFLUOROMETHYLBUTANE OR 1-(4-ETHOXY-3-FLUOROPHENYL)-4-(3-PHENOXYPHENYL)-1-TRIFLUOROMETHYLBUTANE, FOR EXAMPLE; COMBATS INSECTS AND MITES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | claimed |
| US-4791123-A | MITICIDES | SCHERING AKT. (DE) | 1988-12-13 | — | — | US | claimed |