Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560885 | 0.82 | LTA4H (0.42) | LTA4HMAPK1CETPMAPTNPC1 | |
| SCHEMBL7922559 | 0.82 | LTA4H (0.42) | LTA4HMAPK1CETPMAPTNPC1 | |
| SCHEMBL9714189 | 0.80 | CETP (0.48) | LTA4HCETPNPC1CYP1A2CYP3A4 | |
| SCHEMBL10551981 | 0.79 | LTA4H (0.46) | LTA4HMAPK1MAPTNPC1RAB9A | |
| SCHEMBL9714669 | 0.79 | LTA4H (0.41) | LTA4HMAPK1MAPTNPC1RAB9A | |
| SCHEMBL9714640 | 0.78 | LTA4H (0.39) | LTA4HMAPK1MAPTMAPK8MAPK10 | |
| SCHEMBL9804535 | 0.75 | LTA4H (0.41) | LTA4HMAPK1CETPMAPTNPC1 | |
| SCHEMBL9335440 | 0.73 | LTA4H (0.46) | LTA4HMAPK1RAB9AKCNH2CYP1A2 | |
| SCHEMBL10865464 | 0.70 | LTA4H (0.40) | LTA4HMAPK1CETPMAPTNPC1 | |
| SCHEMBL9570732 | 0.70 | MEN1 (0.35) | LTA4HKCNH2L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273549-B1 | INSECTICIDAL THIOETHERS AND DERIVATIVES THEREOF | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-02 | — | — | EP | disclosed |