Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31124935 | 0.93 | TAAR1 (0.48) | TAAR1MAOBCYP19A1AOC3IDO1 | |
| SCHEMBL4047436 | 0.84 | TAAR1 (0.52) | TAAR1MAOBAOC3IDO1LOXL2 | |
| SCHEMBL10574057 | 0.83 | TAAR1 (0.62) | TAAR1MAOBCYP19A1AOC3IDO1 | |
| SCHEMBL10571903 | 0.81 | TAAR1 (0.59) | TAAR1MAOBCYP19A1AOC3IDO1 | |
| SCHEMBL23578345 | 0.81 | TAAR1 (0.45) | TAAR1PTPN2PTPN1PTPN6PTPN11 | |
| SCHEMBL10245015 | 0.81 | TAAR1 (0.45) | TAAR1MAOBCYP19A1AOC3 | |
| SCHEMBL7934895 | 0.81 | IGF1R (0.48) | TAAR1PTPN2PTPN1PTPN6PTPN11 | |
| SCHEMBL9192045 | 0.80 | MAOA (0.52) | MAOB | |
| SCHEMBL31038120 | 0.78 | FAAH (0.55) | MAOB | |
| SCHEMBL28037433 | 0.78 | FAAH (0.55) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37087-E1 | 1-(4-ETHOXYPHENYL)-4-(4-FLUORO-3-PHENOXYPHENYL)-1 -TRIFLUOROMETHYLBUTANE OR 1-(4-ETHOXY-3-FLUOROPHENYL)-4-(3-PHENOXYPHENYL)-1-TRIFLUOROMETHYLBUTANE, FOR EXAMPLE; COMBATS INSECTS AND MITES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | disclosed |