Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 10/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7930475 | 0.90 | FDFT1 (0.52) | FDFT1CETP | |
| SCHEMBL9804343 | 0.89 | FDFT1 (0.58) | FDFT1MAPK14CETP | |
| SCHEMBL7922569 | 0.86 | FDFT1 (0.40) | FDFT1MAPK14PPARGPPARAACP3 | |
| SCHEMBL7922572 | 0.84 | FDFT1 (0.41) | FDFT1MAPK14IDO1TDO2 | |
| SCHEMBL9804456 | 0.83 | FDFT1 (0.54) | FDFT1CETP | |
| SCHEMBL9804670 | 0.83 | FDFT1 (0.56) | FDFT1CETP | |
| SCHEMBL9804487 | 0.83 | CETP (0.49) | FDFT1CETP | |
| SCHEMBL7934874 | 0.82 | FDFT1 (0.53) | FDFT1PPARGPPARACETP | |
| SCHEMBL7931643 | 0.82 | FDFT1 (0.47) | FDFT1CETP | |
| SCHEMBL9804359 | 0.82 | KDM4E (0.50) | FDFT1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37087-E1 | 1-(4-ETHOXYPHENYL)-4-(4-FLUORO-3-PHENOXYPHENYL)-1 -TRIFLUOROMETHYLBUTANE OR 1-(4-ETHOXY-3-FLUOROPHENYL)-4-(3-PHENOXYPHENYL)-1-TRIFLUOROMETHYLBUTANE, FOR EXAMPLE; COMBATS INSECTS AND MITES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | claimed |
| US-4791123-A | MITICIDES | SCHERING AKT. (DE) | 1988-12-13 | — | — | US | claimed |