Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 5/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | ACP3 | P15309 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922565 | 0.86 | FDFT1 (0.53) | FDFT1IDO1TDO2ACP3PPARG | |
| SCHEMBL9570748 | 0.83 | TACR1 (0.42) | IDO1TDO2ACP3PPARGPPARA | |
| SCHEMBL9493734 | 0.83 | CETP (0.40) | FDFT1 | |
| SCHEMBL7929110 | 0.83 | FDFT1 (0.37) | FDFT1 | |
| SCHEMBL7934903 | 0.82 | TTR (0.41) | FDFT1 | |
| SCHEMBL7922572 | 0.81 | FDFT1 (0.41) | FDFT1IDO1TDO2MAPK14TP53 | |
| SCHEMBL407786 | 0.81 | LTA4H (0.41) | FDFT1PPARGPPARASIGMAR1 | |
| SCHEMBL7932383 | 0.81 | FDFT1 (0.37) | FDFT1PPARGPPARASIGMAR1 | |
| SCHEMBL9628951 | 0.80 | MAOA (0.39) | TP53 | |
| SCHEMBL9804252 | 0.80 | FDFT1 (0.35) | FDFT1PPARGPPARASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37087-E1 | 1-(4-ETHOXYPHENYL)-4-(4-FLUORO-3-PHENOXYPHENYL)-1 -TRIFLUOROMETHYLBUTANE OR 1-(4-ETHOXY-3-FLUOROPHENYL)-4-(3-PHENOXYPHENYL)-1-TRIFLUOROMETHYLBUTANE, FOR EXAMPLE; COMBATS INSECTS AND MITES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | claimed |
| US-4791123-A | MITICIDES | SCHERING AKT. (DE) | 1988-12-13 | — | — | US | claimed |