Urea

Urea

SCHEMBL7922672

NC(N)=O.O=C1NCCN1

nearest known ligand 0.38

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 2/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
OR51E2 Q9H255 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KMT2A Q03164 1/20 0.32
MAPK8 P45983 1/20 0.31
CSNK1A1 P48729 1/20 0.31
LIMK1 P53667 1/20 0.31
MAP2K1 Q02750 1/20 0.31
PRKAA1 Q13131 1/20 0.31
DYRK1A Q13627 1/20 0.31
CLK4 Q9HAZ1 1/20 0.31
DYRK1B Q9Y463 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL900591 0.94 CRBN (0.35) CRBNALDH1A1LMNAOR51E2TDP1
Carbamic Acid SCHEMBL7132299 0.91 ACHE (0.41) CRBNKMT2AMAPK8CSNK1A1LIMK1
Urea SCHEMBL19512309 0.89 CRBN (0.32) CRBNALDH1A1LMNAOR51E2TDP1
SCHEMBL20267615 0.88 CRBN (0.35) CRBNKMT2A
Thiourea SCHEMBL11533641 0.85 CRBN (0.36) CRBNKMT2A
Bicarbonate SCHEMBL3127975 0.84 CRBN (0.39) CRBNOR51E2KMT2AMAPK8CSNK1A1
SCHEMBL6274768 0.83
SCHEMBL28169062 0.83 CRBN (0.47) CRBNOR51E2KMT2A
SCHEMBL9827 0.83
Urea SCHEMBL27999458 0.81 ALDH1A1 (0.38) CRBNALDH1A1LMNAOR51E2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102368903-B Soybean event 127 and methods related thereto 巴斯夫农化产品有限公司 2016-10-26 CN disclosed
CN-104789649-A Soybean event 127 and methods related thereto BASF AGROCHEMICAL PRODUCTS BV 2015-07-22 CN disclosed
CN-102368903-A Soybean event 127 and methods related thereto BASF AGROCHEMICAL PRODUCTS BV 2012-03-07 CN disclosed
US-6224795-B1 CONDENSATION OF MELAMINE WITH FORMALDEHYDE FOR RESIN AND METHYL ETHERS IN WATER DISPERSION BASF AKTIENGESELLSCHAFT (DE) 2001-05-01 US disclosed
US-4627875-A INK JETS, ACID DYES, SOLVENT MIXTURE CANON KABUSHIKI KAISHA (JP) 1986-12-09 US disclosed
US-4055412-A Phenylureidoimidazolidinediones as plant protectants E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-10-25 US disclosed