Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL247701 | 0.84 | CA2 (0.44) | CA2CA1ALDH1A1TSHRUSP2 | |
| SCHEMBL6841113 | 0.83 | CA2 (0.63) | CA2CA1ALDH1A1TSHRUSP2 | |
| SCHEMBL1535174 | 0.78 | SOAT1 (0.33) | ALDH1A1SOAT1HSD17B10 | |
| SCHEMBL11882016 | 0.77 | CA2 (0.40) | CA2CA1ALDH1A1TSHRUSP2 | |
| SCHEMBL3182682 | 0.77 | ALDH1A1 (0.45) | CA2CA1ALDH1A1TSHRUSP2 | |
| SCHEMBL4631695 | 0.77 | CA2 (0.40) | CA2CA1ALDH1A1TSHRUSP2 | |
| SCHEMBL390495 | 0.76 | ALDH1A1 (0.38) | CA2CA1ALDH1A1TSHRUSP2 | |
| SCHEMBL11662121 | 0.75 | MGAM (0.46) | CA2CA1ALDH1A1TSHRUSP2 | |
| SCHEMBL20482067 | 0.75 | ALDH1A1 (0.43) | CA2CA1ALDH1A1TSHRUSP2 | |
| SCHEMBL20482049 | 0.75 | ALDH1A1 (0.43) | CA2CA1ALDH1A1TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112851494-B | Preparation method of 1-pyrene butyric acid | 苏州昊帆生物股份有限公司 | 2023-08-15 | — | — | CN | claimed |
| CN-112851494-B | Preparation method of 1-pyrene butyric acid | 苏州昊帆生物股份有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-112851494-A | Preparation method of 1-pyrenebutyric acid | 苏州昊帆生物股份有限公司 | 2021-05-28 | — | — | CN | disclosed |
| US-6268354-B1 | Pharmaceutical composition for antagonizing CCR5 comprising anilide derivative | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| CN-1282326-A | Anilide derivative, process for producing the same, and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-01-31 | — | — | CN | disclosed |
| CN-1282243-A | Pharmaceutical composition containing anilide derivative for antagonizing CCR5 | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-01-31 | — | — | CN | disclosed |