Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | PLEC | Q15149 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28606837 | 0.87 | HTT (0.62) | HTTHIF1AMAPTMEN1KMT2A | |
| SCHEMBL8059082 | 0.79 | HTT (0.53) | HTTHIF1AMAPTMEN1KMT2A | |
| SCHEMBL10054997 | 0.77 | HTT (0.56) | HTTHIF1AMAPTMEN1KMT2A | |
| SCHEMBL4699374 | 0.77 | HIF1A (0.77) | HIF1AMAPTMEN1KMT2AKDM4E | |
| SCHEMBL11831264 | 0.77 | HTT (0.63) | HTTHIF1AMAPTHPGDCYP1A2 | |
| SCHEMBL15249340 | 0.77 | AR (0.51) | HTTMAPTMEN1KMT2AHPGD | |
| SCHEMBL13252936 | 0.74 | LTA4H (0.52) | MAPTHPGDKDM4EALDH1A1GAA | |
| SCHEMBL1624682 | 0.74 | HTT (0.84) | HTTMAPTMEN1KMT2AHPGD | |
| SCHEMBL10184604 | 0.74 | MEN1 (0.60) | HIF1AMAPTMEN1KMT2AHPGD | |
| SCHEMBL6556036 | 0.74 | HIF1A (0.74) | HTTHIF1AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221877-B1 | IN PARTICULAR BOVINE TRICHOMONIASIS AND GIARDIASIS | REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-04-24 | — | — | US | disclosed |