Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31430636 | 0.88 | KMT2A (0.49) | KDM4ETDP1KMT2AMEN1LMNA | |
| SCHEMBL7922447 | 0.88 | TDP1 (0.51) | KDM4EEGFRTDP1KMT2AALDH1A1 | |
| SCHEMBL7928723 | 0.85 | PLA2G2A (0.50) | KDM4EEGFRTDP1ALDH1A1MAPT | |
| SCHEMBL7920254 | 0.85 | PLA2G2A (0.51) | KDM4ECYP2D6EGFRTDP1L3MBTL1 | |
| SCHEMBL8200617 | 0.83 | CHEK1 (0.59) | CHEK1KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7920655 | 0.83 | MRGPRX4 (0.45) | KDM4EEGFRTDP1PTGER4MAPT | |
| SCHEMBL10280565 | 0.82 | MCL1 (0.54) | EGFRLMNASMN1; SMN2PTGER4ALDH1A1 | |
| SCHEMBL4145981 | 0.82 | TDP1 (0.49) | CHEK1KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4304248 | 0.81 | MAPT (0.51) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10279999 | 0.81 | KDM4E (0.51) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010050445-A1 | BICYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2010-05-06 | — | — | WO | disclosed |