Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.60 |
| ▸ | MMP13 | P45452 | 5/20 | 0.60 |
| ▸ | ADAMTS4 | O75173 | 4/20 | 0.60 |
| ▸ | MMP1 | P03956 | 4/20 | 0.60 |
| ▸ | MMP14 | P50281 | 4/20 | 0.60 |
| ▸ | ADAMTS5 | Q9UNA0 | 4/20 | 0.60 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.41 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.41 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.41 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.41 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.41 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3148973 | 0.84 | ADAMTS4 (0.44) | MMP2MMP13ADAMTS4MMP1MMP14 | |
| SCHEMBL3143565 | 0.84 | PSMB5 (0.53) | MMP2MMP13ADAMTS4MMP1MMP14 | |
| SCHEMBL19387780 | 0.84 | ADAMTS4 (0.44) | MMP2MMP13ADAMTS4MMP1MMP14 | |
| SCHEMBL19382404 | 0.84 | PSMB5 (0.53) | MMP2MMP13ADAMTS4MMP1MMP14 | |
| SCHEMBL13381032 | 0.84 | ADAMTS4 (0.44) | MMP2MMP13ADAMTS4MMP1MMP14 | |
| SCHEMBL2512498 | 0.80 | PSMB5 (0.50) | MMP2MMP13ADAMTS4MMP1MMP14 | |
| SCHEMBL3148974 | 0.75 | PSMB5 (0.61) | PSMB5PSMB8PSMB11PSMA7PSMB1 | |
| SCHEMBL19381926 | 0.75 | PSMB5 (0.61) | PSMB5PSMB8PSMB11PSMA7PSMB1 | |
| SCHEMBL3149645 | 0.74 | PSMB5 (0.51) | MMP2ADAMTS4USP30PSMB5PSMB8 | |
| SCHEMBL19381919 | 0.72 | MGLL (0.40) | PSMB5PSMB8PSMB11PSMA7PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036357-A1 | DERIVATIVES OF 1-AMINO-2-CYCLOBUTYLETHYLBORONIC ACID | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-04-01 | — | — | WO | disclosed |