Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30103347 | 0.76 | CYP1A2 (0.47) | CYP1A2CA1CA2LMNATRPV1 | |
| SCHEMBL28915270 | 0.76 | CYP1A2 (0.47) | CYP1A2CA1CA2LMNATRPV1 | |
| SCHEMBL9464901 | 0.76 | ESR1 (0.50) | CYP1A2CA1CA2LMNATYR | |
| SCHEMBL9637976 | 0.76 | CYP1A2 (0.50) | CYP1A2CA1CA2LMNATYR | |
| SCHEMBL277454 | 0.74 | CYP1A2 (0.48) | CYP1A2CA1CA2LMNATYR | |
| SCHEMBL31474575 | 0.74 | CYP1A2 (0.48) | CYP1A2CA1CA2LMNATYR | |
| SCHEMBL17285553 | 0.74 | CYP1A2 (0.48) | CYP1A2CA1CA2LMNATYR | |
| SCHEMBL57086 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ARECQLTSHR | |
| SCHEMBL8920981 | 0.71 | CYP1A2 (0.46) | CYP1A2CA1CA2LMNATRPV1 | |
| SCHEMBL31124864 | 0.71 | GRIN2D (0.46) | CYP1A2CA1CA2LMNATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805132-B1 | Method of producing styrene derivatives | HONSHU CHEMICAL IND (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-5763560-A | TREATING BENZALDEHYDE DERIVATIVE WITH ZINC AND ACTIVE CHLORIDE IN AN ORGANIC SOLVENT | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0805132-A1 | Method of producing styrene derivatives | HONSHU CHEMICAL INDUSTRY CO. LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |