Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932603 | 0.89 | ELANE (0.57) | ELANEPTGDR2CMA1CTSGPRTN3 | |
| SCHEMBL8679946 | 0.81 | ELANE (0.39) | ELANEPTGDR2KMT2A | |
| SCHEMBL16397249 | 0.73 | ELANE (0.53) | ELANEPTGDR2CMA1CTSGPRTN3 | |
| SCHEMBL2257976 | 0.72 | ELANE (0.61) | ELANEPTGDR2CMA1CTSGPRTN3 | |
| SCHEMBL7930188 | 0.71 | ELANE (0.42) | ELANECMA1CTSGPRTN3MEN1 | |
| SCHEMBL24126788 | 0.69 | ELANE (0.56) | ELANEPTGDR2CMA1CTSGPRTN3 | |
| SCHEMBL9824381 | 0.69 | ELANE (0.57) | ELANEPTGDR2CMA1CTSGPRTN3 | |
| SCHEMBL1352319 | 0.68 | ELANE (0.59) | ELANECMA1CTSGPRTN3MEN1 | |
| SCHEMBL8416125 | 0.68 | ELANE (0.55) | ELANEPTGDR2CMA1CTSGPRTN3 | |
| SCHEMBL20804319 | 0.67 | ALDH1A1 (0.58) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800551-B1 | SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS | AKZO NOBEL NV (NL) | 2001-06-13 | — | — | EP | claimed |
| US-5844049-A | Sulfur-vulcanized rubber compositions comprising substituted succinimide compounds | AKZO NOBEL NV (NL) | 1998-12-01 | — | — | US | claimed |