Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30943061 | 0.75 | ELANE (0.57) | ELANECMA1CTSGPRTN3NPSR1 | |
| SCHEMBL7936379 | 0.73 | KMT2A (0.48) | ELANECMA1CTSGNPSR1USP2 | |
| SCHEMBL7923874 | 0.71 | ELANE (0.44) | ELANECMA1CTSGPRTN3MEN1 | |
| SCHEMBL7923401 | 0.70 | KMT2A (0.42) | ELANECMA1CTSGNPSR1USP2 | |
| SCHEMBL821903 | 0.70 | KMT2A (0.48) | ELANECMA1CTSGNPSR1USP2 | |
| SCHEMBL28552779 | 0.64 | AR (0.54) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL19380789 | 0.64 | KMT2A (0.64) | NPSR1USP2LMNATSHRMAPK1 | |
| SCHEMBL7924339 | 0.64 | KMT2A (0.50) | CMA1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL17532466 | 0.64 | ALDH1A1 (0.50) | CMA1LMNATSHRMAPK1MEN1 | |
| SCHEMBL26259824 | 0.64 | ELANE (0.59) | ELANECMA1CTSGPRTN3NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800551-B1 | SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS | AKZO NOBEL NV (NL) | 2001-06-13 | — | — | EP | disclosed |
| US-5844049-A | Sulfur-vulcanized rubber compositions comprising substituted succinimide compounds | AKZO NOBEL NV (NL) | 1998-12-01 | — | — | US | disclosed |