Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928356 | 1.00 | ADRB3 (0.31) | ADRB3ADRA2BADRA2CNPC1GMNN | |
| SCHEMBL12730861 | 0.87 | ADRB3 (0.34) | ADRB3ADRA2BADRA2CNPC1GMNN | |
| SCHEMBL11975703 | 0.87 | ADRB3 (0.34) | ADRB3ADRA2BADRA2CNPC1GMNN | |
| SCHEMBL8212674 | 0.84 | ADRB3 (0.34) | ADRB3ADRA2BADRA2C | |
| SCHEMBL8223794 | 0.84 | ADRB3 (0.34) | ADRB3ADRA2BADRA2C | |
| SCHEMBL8185437 | 0.84 | ADRB3 (0.31) | ADRB3ADRA2BADRA2C | |
| SCHEMBL8247433 | 0.83 | — | — | |
| SCHEMBL6760157 | 0.82 | CTSB (0.31) | — | |
| SCHEMBL2837626 | 0.82 | CTSB (0.31) | — | |
| SCHEMBL8245129 | 0.82 | CTSB (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033466-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C PROTEASE | PHENOMIX CORPORATION (US) | 2010-03-25 | — | — | WO | disclosed |