Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ODC1 | P11926 | 2/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.35 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | ARG1 | P05089 | 2/20 | 0.35 |
| ▸ | ARG2 | P78540 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6567609 | 1.00 | ODC1 (0.37) | ODC1NAALAD2CYP2D6NFKB1BLM | |
| SCHEMBL10659088 | 0.84 | ODC1 (0.37) | ODC1NAALAD2CYP2D6NFKB1BLM | |
| SCHEMBL2823239 | 0.84 | ODC1 (0.37) | ODC1NAALAD2CYP2D6NFKB1BLM | |
| SCHEMBL30410707 | 0.81 | NAALAD2 (0.47) | ODC1NAALAD2CYP2D6NFKB1BLM | |
| SCHEMBL7741623 | 0.80 | CES2 (0.41) | KMT2AMEN1ALDH1A1ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL15799582 | 0.78 | CES2 (0.40) | KMT2AMEN1ALDH1A1ALOX15TSHR | |
| SCHEMBL31023888 | 0.78 | KDM4A (0.40) | NAALAD2LMNAALDH1A1PAOXACLY | |
| Hydrochloric Acid SCHEMBL15799742 | 0.78 | CES2 (0.40) | KMT2AMEN1ALDH1A1ALOX15TSHR | |
| SCHEMBL10912285 | 0.78 | ODC1 (0.42) | ODC1NAALAD2CYP2D6NFKB1BLM | |
| SCHEMBL23845802 | 0.78 | NAALAD2 (0.38) | NAALAD2ACLYFFAR1CPT2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010034029-A1 | PEPTIDOMIMETIC MACROCYCLES | AILERON THERAPEUTICS, INC. (US) | 2010-03-25 | — | — | WO | disclosed |