SCHEMBL7924710

SCHEMBL7924710

CCCCCCCCCCCCCOC(=O)Nc1ccc(C)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.62
RAB9A P51151 7/20 0.62
SMN1; SMN2 Q16637 7/20 0.62
HPGD P15428 3/20 0.62
MAPT P10636 3/20 0.62
ALDH1A1 P00352 3/20 0.62
MAPK1 P28482 2/20 0.62
CASP1 P29466 1/20 0.62
KDM4E B2RXH2 1/20 0.62
MCL1 Q07820 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
TSHR P16473 1/20 0.62
CYP1A2 P05177 1/20 0.58
CYP2C9 P11712 1/20 0.58
CYP2C19 P33261 1/20 0.58
KMT2A Q03164 2/20 0.56
TP53 P04637 1/20 0.56
NFKB1 P19838 1/20 0.56
NFKB2 Q00653 1/20 0.56
RELA Q04206 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14052229 1.00 NPC1 (0.62) NPC1RAB9ASMN1; SMN2HPGDMAPT
SCHEMBL21059214 1.00 NPC1 (0.62) NPC1RAB9ASMN1; SMN2HPGDMAPT
SCHEMBL4840984 1.00 NPC1 (0.62) NPC1RAB9ASMN1; SMN2HPGDMAPT
SCHEMBL21059194 0.98 RAB9A (0.64) NPC1RAB9ASMN1; SMN2HPGDMAPT
SCHEMBL10192215 0.94 RAB9A (0.70) NPC1RAB9ASMN1; SMN2HPGDMAPT
SCHEMBL12411578 0.94 RAB9A (0.69) NPC1RAB9ASMN1; SMN2HPGDMAPT
SCHEMBL13931799 0.93 TSHR (0.56) NPC1RAB9ASMN1; SMN2HPGDMAPT
SCHEMBL13931804 0.93 TSHR (0.56) NPC1RAB9ASMN1; SMN2HPGDMAPT
SCHEMBL13931805 0.93 TSHR (0.56) NPC1RAB9ASMN1; SMN2HPGDMAPT
SCHEMBL12723978 0.92 TSHR (0.67) NPC1RAB9ASMN1; SMN2HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6231784-B1 FOR EXTRACTION OF METAL VALUES, PARTICULARLY COPPER VALUES, IN EXTRACTION FROM AQUEOUS SOLUTIONS, IN WHICH EXTRACTANT AND MODIFIERS ARE EMPLOYED IN ORGANIC SOLVENT PHASE, SOLVENT BEING WATER INSOLUBLE, WATER IMMISCIBLE HYDROCARBON HENKEL CORPORATION 2001-05-15 US claimed
WO-1999054516-A1 MODIFIERS FOR ALDOXIME EXTRACTANT OF METAL VALUES COGNIS CORPORATION (US) 1999-10-28 WO claimed