SCHEMBL7924741

SCHEMBL7924741

O=C(O[Ti]1(OC(=O)c2ccccc2)C2C(=Cc3ccccc32)CCC2=Cc3ccccc3C21)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
F2 P00734 1/20 0.36
TSHR P16473 2/20 0.35
TP53 P04637 1/20 0.35
KMT2A Q03164 5/20 0.34
TDP1 Q9NUW8 2/20 0.34
SLC6A3 Q01959 2/20 0.34
SLC6A2 P23975 1/20 0.34
MEN1 O00255 2/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.32
CHRNA7 P36544 2/20 0.32
GAA P10253 1/20 0.31
MAPK1 P28482 1/20 0.31
HIF1A Q16665 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
HTR3E A5X5Y0 1/20 0.31
HTR3B O95264 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7927198 0.92 LMNA (0.36) LMNAF2TSHRTP53KMT2A
SCHEMBL7919202 0.90 NPC1 (0.35) KMT2ASLC6A3SLC6A2MEN1RAB9A
SCHEMBL7927787 0.83 POLB (0.35) LMNATDP1ALDH1A1POLB
SCHEMBL7924719 0.82 NPC1 (0.35) KMT2ASLC6A3SLC6A2MEN1RAB9A
SCHEMBL7924970 0.80 KCNN4 (0.39)
SCHEMBL7931022 0.80 KMT2A (0.39) KMT2AMEN1GAAALDH1A1POLB
SCHEMBL7925634 0.80 LMNA (0.37) LMNAF2TSHRTP53KMT2A
SCHEMBL7931007 0.80 LMNA (0.33) LMNAKMT2AMEN1MAPK1MAPT
SCHEMBL7925758 0.80 THRB (0.33)
SCHEMBL7927402 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed