SCHEMBL7925046

SCHEMBL7925046

O=C(O[Ti](OC(=O)c1cccc2ccccc12)(C1C=Cc2ccccc21)C1C=Cc2ccccc21)c1cccc2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
NR4A1 P22736 1/20 0.40
NR4A2 P43354 1/20 0.40
NR4A3 Q92570 1/20 0.40
MMP3 P08254 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
CDC25B P30305 2/20 0.36
KDM4E B2RXH2 4/20 0.36
HPGD P15428 4/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
PTPN1 P18031 1/20 0.36
PLK1 P53350 1/20 0.36
ALDH1A1 P00352 4/20 0.36
MEN1 O00255 4/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
ATM Q13315 1/20 0.36
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7919431 0.90 KMT2A (0.41) KMT2APOLBGAANR4A1NR4A2
SCHEMBL28872350 0.80 KMT2A (0.43) KMT2APOLBGAANR4A1NR4A2
SCHEMBL7927363 0.78 LMNA (0.39) KMT2APOLBALDH1A1MEN1SMN1; SMN2
SCHEMBL7927122 0.76 POLB (0.42) KMT2APOLBKDM4EHPGDALDH1A1
SCHEMBL7925550 0.76 KMT2A (0.44) KMT2APOLBGAANR4A1NR4A2
SCHEMBL7925501 0.74 NPC1 (0.37) KMT2APOLBKDM4EMEN1SMN1; SMN2
SCHEMBL7927285 0.72 KMT2A (0.42) KMT2APOLBGAANR4A1NR4A2
SCHEMBL7930266 0.72 NR4A1 (0.57) KMT2APOLBGAANR4A1NR4A2
SCHEMBL7919512 0.72 RET (0.36) POLBALDH1A1SMN1; SMN2MAPTLMNA
SCHEMBL7931030 0.71 RET (0.37) POLBSMN1; SMN2LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed