SCHEMBL7927122

SCHEMBL7927122

CC(=O)O[Ti](OC(C)=O)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.42
RET P07949 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
BRD4 O60885 1/20 0.32
CCL2 P13500 1/20 0.32
MAPT P10636 2/20 0.31
HTR6 P50406 1/20 0.31
ALDH1A1 P00352 4/20 0.31
KDM4E B2RXH2 2/20 0.31
HTR2A P28223 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ATM Q13315 1/20 0.31
CYP2D6 P10635 1/20 0.30
P2RX4 Q99571 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7919128 0.89 POLB (0.41) POLBRETSMN1; SMN2LMNAMEN1
SCHEMBL7919463 0.86 POLB (0.34) POLB
SCHEMBL7927802 0.84 ELANE (0.33) POLBLMNAMAPTALDH1A1TDP1
SCHEMBL7931030 0.84 RET (0.37) POLBRETSMN1; SMN2LMNAHTR6
SCHEMBL7927363 0.83 LMNA (0.39) POLBSMN1; SMN2LMNAMEN1KMT2A
SCHEMBL7919512 0.82 RET (0.36) POLBRETSMN1; SMN2LMNAMAPT
SCHEMBL7924994 0.81 THRB (0.32) HTR6
SCHEMBL7931102 0.81 ATM (0.31) ATM
SCHEMBL8155332 0.79 POLB (0.37) POLBRETSMN1; SMN2LMNAMEN1
SCHEMBL7931012 0.79 KCNN4 (0.41) ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed