Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11586498 | 0.86 | KMT2A (0.47) | THRATHRBALDH1A1KDM4EMAPT | |
| SCHEMBL19594430 | 0.85 | THRA (0.54) | THRATHRBALDH1A1KDM4EKMT2A | |
| SCHEMBL91939 | 0.82 | FFAR4 (0.33) | THRATHRBALDH1A1GAAKDM4E | |
| SCHEMBL27458128 | 0.82 | KMT2A (0.50) | THRATHRBALDH1A1KDM4EMAPT | |
| SCHEMBL28101608 | 0.77 | PTGS1 (0.34) | THRATHRBALDH1A1GAAKDM4E | |
| SCHEMBL2243051 | 0.77 | THRA (0.38) | THRATHRBALDH1A1KDM4EMAPT | |
| SCHEMBL1991553 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTHSD17B10KMT2A | |
| SCHEMBL29712140 | 0.75 | KDM4E (0.39) | ALDH1A1GAAKDM4EMAPTHPGD | |
| SCHEMBL11586422 | 0.74 | KMT2A (0.46) | THRATHRBALDH1A1KDM4EMAPT | |
| Ammonia Solution, Strong SCHEMBL8858388 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228688-B1 | Flip-chip resin-encapsulated semiconductor device | KABUSHIKI KAISHA TOSHIBA (JP) | 2001-05-08 | — | — | US | disclosed |