Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7925286 | 0.81 | EPHX2 (0.36) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6154684 | 0.78 | SIGMAR1 (0.35) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6155151 | 0.76 | SIGMAR1 (0.36) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6156180 | 0.73 | EPHX2 (0.37) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9113853 | 0.66 | SIGMAR1 (0.40) | SIGMAR1EPHX2 | |
| SCHEMBL7934716 | 0.64 | EPHX2 (0.46) | EPHX2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL6154914 | 0.62 | EPHX2 (0.52) | EPHX2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL8843172 | 0.61 | GRIN2D (0.35) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8731825 | 0.60 | EPHX2 (0.54) | EPHX2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL8342119 | 0.60 | EPHX2 (0.44) | EPHX2MEN1HTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242198-B1 | ADMINISTERING GUANIDINE COMPOUND | CAMBRIDGE NEUROSCIENCE, INC. | 2001-06-05 | — | — | US | disclosed |