Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 5/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846224 | 0.84 | RECQL (0.55) | RECQLCSNK2A1PDE4APDE4DPDE4B | |
| SCHEMBL7043742 | 0.82 | BIRC5 (0.49) | PPARGHTTPDE4APDE4DPDE4B | |
| SCHEMBL7376963 | 0.82 | HTT (0.52) | RECQLCSNK2A1HTTPDE4APDE4D | |
| SCHEMBL134754 | 0.81 | RECQL (0.67) | RECQLCSNK2A1PDE4APDE4DPDE4B | |
| SCHEMBL2958828 | 0.79 | RECQL (0.60) | RECQLPDE4APDE4DPDE4BPDE4C | |
| SCHEMBL7928047 | 0.78 | PDE4A (0.52) | PDE4APDE4DPDE4BPDE4CMAPK1 | |
| SCHEMBL8845989 | 0.78 | S1PR1 (0.49) | PPARGHTT | |
| SCHEMBL7920527 | 0.77 | PPARG (0.37) | RECQLPPARGCSNK2A1PDE4APDE4D | |
| SCHEMBL10996676 | 0.76 | S1PR1 (0.51) | HTT | |
| SCHEMBL8846068 | 0.76 | S1PR1 (0.51) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076564-A2 | ISOCHROMENONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |