Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 5/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7925295 | 0.83 | CYP1A2 (0.41) | CYP1A2CYP2D6CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL7932570 | 0.81 | PPARG (0.37) | PPARGPPARDPPARANPY1RNPY2R | |
| SCHEMBL7926092 | 0.80 | PDE4A (0.39) | PPARGPPARDPPARAPDE4APDE4B | |
| SCHEMBL7922511 | 0.79 | SMPD1 (0.45) | CYP1A2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7920336 | 0.77 | PDE4A (0.55) | POLBCYP1A2PDE4APDE4BPDE4C | |
| SCHEMBL7925327 | 0.77 | RECQL (0.48) | PPARGPPARDPPARACYP1A2PDE4A | |
| SCHEMBL28748440 | 0.77 | CHUK (0.44) | ALDH1A1 | |
| SCHEMBL3758134 | 0.77 | CHUK (0.44) | ALDH1A1 | |
| SCHEMBL29607397 | 0.77 | CHUK (0.44) | ALDH1A1 | |
| SCHEMBL21741408 | 0.75 | KDM4E (0.39) | PPARGPPARDPPARAPOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076564-A2 | ISOCHROMENONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |