SCHEMBL7925352

SCHEMBL7925352

CCCO[SiH](C1CCCCC1)C1CCCC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.33
ADH1A P07327 1/20 0.31
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
SHBG P04278 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2859809 0.98 CYP1A2 (0.31) CYP1A2CYP2D6CYP2C19
SCHEMBL1314192 0.82 CYP1A2 (0.33) CYP1A2ADH1ACYP2D6CYP2C19SHBG
SCHEMBL4762805 0.81 SHBG (0.32) CYP1A2SHBG
SCHEMBL1169448 0.79 CYP1A2 (0.31) CYP1A2CYP2D6CYP2C19
SCHEMBL2851829 0.78
SCHEMBL27595320 0.77
SCHEMBL23521454 0.74
SCHEMBL3275670 0.73 ALDH1A1 (0.36) CYP1A2ADH1ACYP2D6CYP2C19SHBG
SCHEMBL3006349 0.72 EPHX1 (0.32)
SCHEMBL11784826 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0790257-B1 SOLID CATALYTIC COMPONENT AND CATALYST FOR POLYMERIZING OLEFINS TOHO TITANIUM CO LTD (JP) 2001-11-14 EP disclosed
US-5932510-A AN OLEFIN POLYMERIZATION CATALYST CONSISTS OF THE REACTION PRODUCT OF DIALKOXYMAGNESIUM OR DIARYLOXYMAGNESIUM, HALOALKOXYTITANIUM OR HALOGENATED TITANIUM, A DIESTER OF PHTHALIC ACID, A CYCLIC OR CHAIN POLYSILOXANE TOHO TITANIUM CO., LTD. (JP) 1999-08-03 US disclosed
EP-0790257-A1 SOLID CATALYTIC COMPONENT AND CATALYST FOR POLYMERIZING OLEFINS TOHO TITANIUM CO., LTD. (JP) 1997-08-20 EP disclosed