SCHEMBL7925356

SCHEMBL7925356

CCC(O[SiH3])C1(C2CCCCC2)CCCC1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.33
CYP3A4 P08684 2/20 0.32
ABCB11 O95342 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
CYP2D6 P10635 1/20 0.32
CHRM1 P11229 1/20 0.32
CYP2C9 P11712 1/20 0.32
TSHR P16473 1/20 0.32
CHRM3 P20309 1/20 0.32
DRD1 P21728 1/20 0.32
HRH2 P25021 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32
SCN1A P35498 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3090787 0.76 SHBG (0.38) SHBGCYP3A4ABCB11LMNACYP1A2
SCHEMBL28845544 0.71 SHBG (0.32) SHBG
SCHEMBL8018898 0.69
SCHEMBL10888621 0.69
SCHEMBL3095782 0.69
SCHEMBL24063231 0.67
SCHEMBL13463209 0.67 CYP3A4 (0.32) CYP3A4ABCB11LMNACYP1A2CHRM2
SCHEMBL13442991 0.66 ATP1A1 (0.33) HSD17B10
SCHEMBL11796959 0.65
SCHEMBL9446385 0.65 KDM4E (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0790257-B1 SOLID CATALYTIC COMPONENT AND CATALYST FOR POLYMERIZING OLEFINS TOHO TITANIUM CO LTD (JP) 2001-11-14 EP disclosed
US-5932510-A AN OLEFIN POLYMERIZATION CATALYST CONSISTS OF THE REACTION PRODUCT OF DIALKOXYMAGNESIUM OR DIARYLOXYMAGNESIUM, HALOALKOXYTITANIUM OR HALOGENATED TITANIUM, A DIESTER OF PHTHALIC ACID, A CYCLIC OR CHAIN POLYSILOXANE TOHO TITANIUM CO., LTD. (JP) 1999-08-03 US disclosed
EP-0790257-A1 SOLID CATALYTIC COMPONENT AND CATALYST FOR POLYMERIZING OLEFINS TOHO TITANIUM CO., LTD. (JP) 1997-08-20 EP disclosed