SCHEMBL7925359

SCHEMBL7925359

O=C(O)[C@@H]1CCCN(CCOCCC(c2ccccc2)c2cccc(C(F)(F)F)c2)C1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC6A1 P30531 4/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7925361 1.00 SLC6A1 (0.58) SLC6A1
Hydrochloric Acid SCHEMBL7917369 0.99 SLC6A1 (0.57) SLC6A1
Hydrochloric Acid SCHEMBL7917366 0.99 SLC6A1 (0.57) SLC6A1
SCHEMBL7923659 0.89 ALDH1A1 (0.59) SLC6A1
SCHEMBL7923661 0.89 ALDH1A1 (0.59) SLC6A1
SCHEMBL7923164 0.88 SLC6A1 (0.58) SLC6A1
SCHEMBL7923127 0.88 SLC6A1 (0.58) SLC6A1
SCHEMBL7925377 0.88 SLC6A1 (0.65) SLC6A1
SCHEMBL7925381 0.88 SLC6A1 (0.65) SLC6A1
Hydrochloric Acid SCHEMBL7917236 0.87 SLC6A1 (0.57) SLC6A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6174898-B1 TREATING FILARIAE IN LYMPHATIC SYSTEM BY ADMINISTERING N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS IN WHICH A SUBSTITUTED ALKYL CHAIN FORMS PART OF N-SUBSTITUENT AND SALTS NOVO NORDISK A/S (DK) 2001-01-16 US claimed
US-5198451-A Treatment of epilepsy, inhibitors of gamma-aminobutyric acid uptake from synaptic cleft NOVO NORDISK A/S (DK) 1993-03-30 US claimed
EP-0502031-A1 N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND A PHARMACEUTICAL COMPOSITION. NOVO NORDISK AS (DK) 1992-09-09 EP claimed
WO-1991007389-A1 N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND A PHARMACEUTICAL COMPOSITION NOVO NORDISK A/S (DK) 1991-05-30 WO claimed