SCHEMBL7925614

SCHEMBL7925614

O=C(O[Ti](OC(=O)C(c1ccccc1)(c1ccccc1)c1ccccc1)(OC(=O)C(c1ccccc1)(c1ccccc1)c1ccccc1)C1C=Cc2ccccc21)C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.41
ATM Q13315 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7931012 0.89 KCNN4 (0.41) KCNN4ATM
SCHEMBL7925544 0.83 ELANE (0.33) MEN1KMT2A
SCHEMBL7928436 0.78 LMNA (0.39) ATMMEN1KMT2A
SCHEMBL7919128 0.78 POLB (0.41) ATMMEN1KMT2A
SCHEMBL7919144 0.74 ATM (0.31) ATM
SCHEMBL7925031 0.74 THRB (0.32)
SCHEMBL7925610 0.74 RET (0.37) MEN1KMT2A
SCHEMBL7919309 0.74 KCNN4 (0.46) KCNN4ATMMEN1KMT2A
SCHEMBL7928317 0.73 POLB (0.34) MEN1KMT2A
SCHEMBL7927256 0.72 RET (0.36) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed