Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 6/20 | 0.62 |
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1160282 | 0.83 | DPP4 (0.67) | CCR3MC4RTSHRMAPTMEN1 | |
| SCHEMBL18840883 | 0.77 | CCR3 (1.00) | CCR3TSHRMEN1KMT2ATP53 | |
| SCHEMBL7936488 | 0.76 | TACR1 (0.61) | CCR3TSHRALDH1A1POLB | |
| SCHEMBL7925939 | 0.75 | MAPT (0.55) | CCR3TSHRMAPTLMNAMEN1 | |
| SCHEMBL18840849 | 0.75 | CCR3 (1.00) | CCR3MAPTLMNAMEN1KMT2A | |
| SCHEMBL7925962 | 0.74 | CCR3 (0.55) | CCR3TSHRMAPTLMNAMEN1 | |
| SCHEMBL16501809 | 0.74 | CCR3 (0.49) | CCR3TSHRMAPTLMNAMEN1 | |
| SCHEMBL4382187 | 0.74 | CCR3 (0.52) | CCR3MC4RTSHRMAPTLMNA | |
| SCHEMBL14593237 | 0.74 | ABCB1 (0.45) | CCR3MC4RMEN1KMT2AKDM4E | |
| SCHEMBL20534579 | 0.72 | PTGFR (0.51) | CCR3TSHRKMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235732-B1 | RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-22 | — | — | US | disclosed |
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | disclosed |
| US-5985881-A | TREATMENT AND PREVENTION OF RESPIRATORY DISORDERS, INFLAMMATORY EYE DISEASES, INFLAMMATORY SKIN DISEASES, INTESTINAL DISORDERS, OTHER INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM KG (DE) | 1999-11-16 | — | — | US | disclosed |
| US-5708006-A | ANTIINFLAMMATORY AGENTS | BOEHRINGER INGELHEIM KG (DE) | 1998-01-13 | — | — | US | disclosed |
| US-5696123-A | ALPHA-PIPERAZINYL BENZYL COMPOUND AS TACHYKININ ANTAGONIST TREATING ASTHMA, BRONCHITIS, SKIN DISORDER, EYE DISEASE, HEADACHE, GASTROINTESTINAL DISORDER | BOEHRINGER INGELHEIM KG (DE) | 1997-12-09 | — | — | US | disclosed |
| EP-0781277-A1 | NEUROKININ ANTAGONISTS | BOEHRINGER INGELHEIM KG (DE) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996008480-A1 | NEUROKININ ANTAGONISTS | BOEHRINGER INGELHEIM KG (DE) | 1996-03-21 | — | — | WO | disclosed |