Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.65 |
| ▸ | CA2 | P00918 | 4/20 | 0.65 |
| ▸ | CA12 | O43570 | 3/20 | 0.65 |
| ▸ | CA7 | P43166 | 3/20 | 0.65 |
| ▸ | CA9 | Q16790 | 3/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.65 |
| ▸ | XDH | P47989 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921827 | 0.87 | CA1 (0.67) | CA1CA2CA12CA7CA9 | |
| SCHEMBL13847151 | 0.84 | CA1 (0.67) | CA1CA2CA12CA7CA9 | |
| SCHEMBL13955372 | 0.82 | CA1 (0.65) | CA1CA2CA12CA7CA9 | |
| SCHEMBL5924534 | 0.82 | MAPT (0.64) | CA1CA2CA12CA7CA9 | |
| SCHEMBL3272963 | 0.82 | MAPT (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7922998 | 0.81 | MAPT (0.49) | CA1CA2CA12CA7CA9 | |
| SCHEMBL1117999 | 0.81 | PDK1 (0.56) | CA1CA2CA12CA7CA9 | |
| SCHEMBL22212169 | 0.81 | KDM4E (0.49) | CA1CA2CA12CA7CA9 | |
| SCHEMBL6261199 | 0.81 | XDH (0.62) | CA1CA2CA12CA7CA9 | |
| SCHEMBL2080524 | 0.81 | NOTUM (0.55) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010050445-A1 | BICYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2010-05-06 | — | — | WO | disclosed |