Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | RARG | P13631 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | GOT1 | P17174 | 1/20 | 0.41 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920676 | 0.90 | IKBKB (0.42) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL7920725 | 0.89 | RARG (0.54) | RARARARBRARGMEN1NR1I2 | |
| Hydrochloric Acid SCHEMBL7929378 | 0.88 | RARG (0.53) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL7102156 | 0.86 | RARA (0.44) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL8459019 | 0.86 | IKBKB (0.39) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL7927661 | 0.82 | KMT2A (0.42) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL8459847 | 0.81 | IKBKB (0.46) | RARARARBRARGMEN1NR1I2 | |
| Hydrochloric Acid SCHEMBL8457480 | 0.81 | IKBKB (0.45) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL7096456 | 0.79 | RARG (0.49) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL8459021 | 0.74 | RARA (0.44) | RARARARBRARGMEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225328-B1 | FOR THERAPY OF DISORDERS OR AILMENTS RELATED TO AN OVERREGULATION OF RETINOIC ACID RECEPTORS AND/OR TO HYPERVIAMINOSIS A | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-05-01 | — | — | US | disclosed |