Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.37 |
| ▸ | RARG | P13631 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.37 |
| ▸ | GOT1 | P17174 | 1/20 | 0.37 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459847 | 0.88 | IKBKB (0.46) | IKBKBIDO1TDO2RARAMEN1 | |
| Hydrochloric Acid SCHEMBL8457480 | 0.87 | IKBKB (0.45) | IKBKBIDO1TDO2RARAMEN1 | |
| SCHEMBL7926568 | 0.86 | RARA (0.41) | IKBKBIDO1TDO2RARAMEN1 | |
| SCHEMBL7102156 | 0.82 | RARA (0.44) | IKBKBRARAMEN1KMT2ARARB | |
| SCHEMBL7920725 | 0.81 | RARG (0.54) | IKBKBRARAMEN1KMT2ARARB | |
| Hydrochloric Acid SCHEMBL7929378 | 0.80 | RARG (0.53) | IKBKBRARAMEN1KMT2ARARB | |
| SCHEMBL7096456 | 0.78 | RARG (0.49) | IKBKBIDO1TDO2RARAMEN1 | |
| SCHEMBL7920676 | 0.77 | IKBKB (0.42) | IKBKBIDO1TDO2RARAMEN1 | |
| SCHEMBL8459021 | 0.75 | RARA (0.44) | IKBKBRARAMEN1KMT2ARARB | |
| SCHEMBL7927661 | 0.74 | KMT2A (0.42) | IKBKBTDO2RARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952382-A | INHIBITING THE BIOLOGICAL EFFECTS OF AN OVERREGULATION OF RETINOID ACID RECEPTORS AND/OR OF A HYPERVITAMINOSIS A; TREATING SKIN DISORDER, EYE VISION DEFECTS, SKIN AGING | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-09-14 | — | — | US | disclosed |