Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.38 |
| ▸ | WNT3A | P56704 | 2/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120514 | 0.86 | CYP2A6 (0.41) | HSD17B10ALDH1A1KDM4EHPGDENPP2 | |
| SCHEMBL143239 | 0.81 | CDK8 (0.44) | HSD17B10ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL18032995 | 0.79 | CA12 (0.53) | HSD17B10ALDH1A1KDM4EHPGDENPP2 | |
| SCHEMBL15683163 | 0.79 | KDM4E (0.47) | HSD17B10ALDH1A1KDM4EHPGDENPP2 | |
| SCHEMBL121721 | 0.79 | CYP2D6 (0.50) | HSD17B10ALDH1A1KDM4EHPGDENPP2 | |
| SCHEMBL15971144 | 0.79 | KDM4E (0.47) | HSD17B10ALDH1A1KDM4EHPGDENPP2 | |
| SCHEMBL3714107 | 0.77 | ASH1L (0.39) | IKBKBCHUKCYP1A2SMN1; SMN2 | |
| SCHEMBL1144962 | 0.76 | MEN1 (0.41) | HSD17B10ALDH1A1KDM4EHPGDTPMT | |
| SCHEMBL15970869 | 0.75 | XDH (0.44) | HSD17B10ALDH1A1KDM4EHPGDENPP2 | |
| SCHEMBL1997793 | 0.73 | ALOX15 (0.45) | KEAP1IKBKBCHUKMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115417804-A | Synthesis method of 7-methyl-1H-indole-5-carboxylic acid | 天津药明康德新药开发有限公司 | 2022-12-02 | — | — | CN | claimed |
| US-20250313574-A1 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2025-10-09 | — | — | US | disclosed |
| EP-4562017-A1 | NOVEL ACC INHIBITORS | Pfizer Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| CN-120019059-A | Novel ACC inhibitors | 辉瑞公司 | 2025-05-16 | — | — | CN | disclosed |
| EP-4536653-A2 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | Eisai R&D Management Co., Ltd. (JP) | 2025-04-16 | — | — | EP | disclosed |
| US-20240109915-A1 | NOVEL ACC INHIBITORS | PFIZER INC. (US) | 2024-04-04 | — | — | US | disclosed |
| WO-2024023727-A1 | NOVEL ACC INHIBITORS | PFIZER INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| WO-2023239906-A2 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2023-12-14 | — | — | WO | disclosed |
| CN-115417804-A | Synthesis method of 7-methyl-1H-indole-5-carboxylic acid | 天津药明康德新药开发有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-115417804-A | Synthesis method of 7-methyl-1H-indole-5-carboxylic acid | 天津药明康德新药开发有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-115417804-A | Synthesis method of 7-methyl-1H-indole-5-carboxylic acid | 天津药明康德新药开发有限公司 | 2022-12-02 | — | — | CN | disclosed |
| US-6228868-B1 | ANTICARCINOGENIC AND ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-08 | — | — | US | disclosed |
| WO-2000006556-A1 | SUBSTITUTED OXAZOLINES AS ANTIPROLIFERATIVE AGENTS | ABBOTT LABORATORIES (US) | 2000-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313574-A1 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | NEU1, NEU2, NEU4 | HSD17B10 1624/4885ALDH1A1 474/4885KDM4E 4207/4885 |
| US-20240109915-A1 | NOVEL ACC INHIBITORS | CBR3, NAT1, ACACB | HSD17B10 102/4885ALDH1A1 2330/4885KDM4E 4784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.