SCHEMBL7926899

SCHEMBL7926899

CCCCc1ccc(C=O)c(O[SiH](C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.40
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
SKP2 Q13309 1/20 0.37
LTA4H P09960 3/20 0.37
HTR1A P08908 3/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2D6 P10635 2/20 0.36
LMNA P02545 1/20 0.36
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TSHR P16473 1/20 0.36
TUBA1B P68363 1/20 0.36
TUBA4A P68366 1/20 0.36
TUBB4B P68371 1/20 0.36
TUBB3 Q13509 1/20 0.36
TUBB2A Q13885 1/20 0.36
HIF1A Q16665 1/20 0.36
TUBB8 Q3ZCM7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8710220 0.85 SKP2 (0.37) PPARGPPARASKP2LTA4HHTR1A
SCHEMBL31455942 0.83 ALDH1A1 (0.53) CDK1PPARGPPARALTA4HHTR1A
SCHEMBL27002142 0.79 PPARG (0.57) CDK1PPARGPPARALTA4HHTR1A
SCHEMBL1446176 0.78 PPARG (0.41) CDK1PPARGPPARASKP2LTA4H
SCHEMBL31455929 0.78 PPARG (0.59) CDK1PPARGPPARALTA4HHTR1A
SCHEMBL31442610 0.78 PPARG (0.59) CDK1PPARGPPARALTA4HHTR1A
SCHEMBL31442707 0.77 PPARA (0.48) CDK1PPARGPPARAL3MBTL1THRB
SCHEMBL31442640 0.77 PPARA (0.48) CDK1PPARGPPARAL3MBTL1THRB
SCHEMBL28038475 0.77 PPARA (0.51) CDK1PPARGPPARATHRB
SCHEMBL16901836 0.74 SKP2 (0.56) CDK1SKP2CYP1A2CYP2D6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805132-B1 Method of producing styrene derivatives HONSHU CHEMICAL IND (JP) 2001-12-12 EP disclosed
US-5763560-A TREATING BENZALDEHYDE DERIVATIVE WITH ZINC AND ACTIVE CHLORIDE IN AN ORGANIC SOLVENT HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 1998-06-09 US disclosed
EP-0805132-A1 Method of producing styrene derivatives HONSHU CHEMICAL INDUSTRY CO. LTD. (JP) 1997-11-05 EP disclosed