SCHEMBL7926980

SCHEMBL7926980

CC1=C([Ti](C)(C)NC(C)(C)C)C(C)c2ccc3c(ccc4ccccc43)c21.[SiH4]

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.35
ALDH1A1 P00352 3/20 0.31
CYP1A2 P05177 2/20 0.31
HPGD P15428 2/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
ALOX12 P18054 1/20 0.31
MAPK1 P28482 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 2/20 0.31
CYP2A6 P11509 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7935735 0.73 HPRT1 (0.33) HPRT1ALDH1A1CYP1A2HPGDMEN1
SCHEMBL7926994 0.72 HPRT1 (0.35) HPRT1ALDH1A1CYP1A2HPGDMEN1
SCHEMBL7926905 0.71 HPRT1 (0.36) HPRT1ALDH1A1CYP1A2HSD17B10CYP2A6
Hydrochloric Acid SCHEMBL7170194 0.63 MAPT (0.33)
SCHEMBL7598418 0.61
Chrysene SCHEMBL9786466 0.59 HPRT1 (1.00) HPRT1ALDH1A1CYP1A2HPGDMEN1
SCHEMBL25510 0.59 HPRT1 (1.00) HPRT1ALDH1A1CYP1A2HPGDMEN1
SCHEMBL31177955 0.59 HPRT1 (1.00) HPRT1ALDH1A1CYP1A2HPGDMEN1
Chrysene SCHEMBL384031 0.59 HPRT1 (1.00) HPRT1ALDH1A1CYP1A2HPGDMEN1
Chrysene SCHEMBL29792076 0.59 HPRT1 (1.00) HPRT1ALDH1A1CYP1A2HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6329486-B1 PHYSICAL PROPERTIES THE DOW CHEMICAL COMPANY 2001-12-11 US disclosed